Abstract Introduction: Neovascular glaucoma (NVG) is an aggressive glaucoma subtype of difficult management. Cyclodestructive procedures are a viable treatment option and diode láser ablation has been reported to be effective and safe. The purpose of this study was to evalua-te the effectiveness and safety profile of diode láser cyclophotocoagulation in diabetic NVG. Methods: Ambispective case-control study of 38 eyes (19 control group CG, 19 study group TG). Success was defined as intraocular pressure (IOP) < 22 mmHg or a 30% reduction from baseline. Intraocular pressure. © 2012 Sociedad Mexicana de Oftalmología.