Analysis of the HIV/AIDS disease burden in Mexico (1995-2021): progress in mortality and challenges in prevention Análisis de la carga de la enfermedad por VIH/SIDA en México (1995-2021): avances en mortalidad y desafíos en prevención
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Background: Human immunodeficiency virus (HIV) infection and aquired immune deficiency syndrome (AIDS) is a public health problem in Mexico. The publication of the estimates from the Global Burden of Disease (GBD) study 2021 represents a valuable opportunity to assess the evolution of the epidemic in the country. Objective: To analyze the evolution of HIV/AIDS incidence and mortality in Mexico from 1995 to 2021. Material and methods: The HIV/AIDS burden was evaluated using incidence and mortality indicators, utilizing the estimates from the GBD 2021 from 1995 to 2021. Results: The age-standardized HIV incidence rate in Mexico increased by 64%, rising from 7.7 to 12.6 new cases per 100,000 inhabitants. In contrast, the age-standardized mortality rate decreased by 30%, from 5.7 to 4.0 deaths per 100,000 inhabitants. Significant differences in incidence and mortality trends were observed across federal entities, age groups, and sexes. Conclusions: Despite the notable reduction in HIV/AIDS mortality, incidence has shown a sustained increase since 1995, especially among older adults and young people. These trends raise questions regarding the effectiveness of the preventive strategies implemented in Mexico over the past three decades. © 2025 Academia Nacional de Medicina de México, A.C.
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