The transition toward electrified transportation may reduce the long-term demand for fuel ethanol, creating both challenges and opportunities for the Brazilian bioeconomy. This study evaluates the strategic valorization of ethanol through the production of high-value bioproducts. A multi-criteria mixed integer nonlinear programming model is developed to design an integrated supply chain comprising representative biorefineries, ethanol-derived production plants, maritime hubs, and local and international markets. Economic performance, greenhouse gas emissions, water and energy consumption, and social equity are evaluated across 30 weighting scenarios. The results indicate that export-oriented configurations can generate positive economic returns and support the use of ethanol as a chemical feedstock. Road freight is the main source of modeled emissions, whereas water and energy requirements strongly influence technology selection, production scale, and product portfolios. Under the assumed redistribution mechanism, the model projects population-weighted regional reductions of approximately 0.1¿2.4% in the Gini index and 0.2¿3.7% in social vulnerability, depending on the region and scenario. Overall, the results demonstrate that, under the adopted assumptions, ethanol-derived value chains can support a sustainable and socially inclusive bioeconomy while providing alternative valorization pathways for ethanol under changing market conditions.
