Prevalence and clinical manifestations of chronic anterior uveitis in Mexican patients with juvenile idiopathic arthritis Prevalencia y manifestaciones cl¡nicas de la uve¡tis anterior cr¢nica en pacientes mexicanos con artritis idiop tica juvenil
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Objective: To analyze the systemic clinical manifestations and the anterior chronic uveitis associated, in Mexican patients with Juvenile Idiopathic Arthritis (JIA). Methods: Longitudinal and observational study that included all patients diagnosed with JIA between July 1994 and February 2010. We reviewed data of patients with JIA with descriptive statistics. The relative risk of developing Uveitis according to arthritis characteristics was analyzed by univariate analysis and multivariate logistic regression model. Results: A total of 98 patients with JIA were included. The prevalence of uveitis was 16.3% (CI = 10.3 a 24.8). The oligoarticular form was more common in cases of uveitis (P = 0.008). The percentage of patients with positive ANA (antinuclear antibody) was higher in the uveitis group compared with those without uveitis (P = 0.049). Cases with oligoarticular form are at increased risk, OR = 4.41 (CI = 1.24 - 15.75) for developing intraocular inflammation; while patients with a negative ANA were at lower risk, OR = 0.28 (CI = 0.06 a 1.3). Ocular complications affected 55.2% of eyes with uveitis, the most common being: posterior synechiae, band keratopathy, cataract and glaucoma. Conclusions: The prevalence of uveitis in Mexican JIA patients is similar to that reported in the literature. It was also found that the uveitis is more common in girls with the oligoarticular type of arthritis, who started with the first clinical manifestations of the disease in early age and had positive ANA. The ocular complications related to chronic uveitis found in this study were consistent with those reported previously by other authors. © 2011 Sociedad Mexicana de Oftalmología.