abstract
- © 2018 Sociedad Mexicana de Urologia. Colegio de Profesionistas A.C.. All rights reserved.OBJECTIVE: To report our experience with the surgical treatment and histopathologic characteristics of patients with renal cell carcinoma at a hospital in Northern Mexico. MATERIALS AND METHODS: A descriptive, cross-sectional study was conducted through the review of the case records of patients operated on for kidney tumor. Radical or partial nephrectomy was decided upon, according to the nephrometry score from contrast-enhanced abdominal tomography and the criterion of the surgeon. The comorbidities evaluated were: High blood pressure, type 2 diabetes mellitus, gross hematuria, flank pain, and increased volume in the hypochondrium. Glomerular filtration rate was registered before surgery and 15 days after the procedure and was calculated using the Modification of Diet in Renal Disease (MDRD) formula. Variables were analyzed using measures of central tendency and survival was assessed through the Kaplan- Meier curves. RESULTS: Eighty-nine cases were registered. Symptoms presented in 74% the most common of which were hematuria and flank pain. Radical nephrectomy predominated, and the mean pathologic tumor size was 6.7 cm. A total of 84% of the cases had stage T1b to T4 disease. Estimated 5-year cancer-specific survival for all stages was 90% and recurrence-free survival for organ-confined stages was 83.1%. The type of surgery had no statistical influence on postoperative kidney function (p = 0.33). CONCLUSION: The histopathologic characteristics, treatment, and survival in patients with kidney cancer were similar to those reported in other countries.