Successful pharmaco-invasive approach using a lower alteplase dose and VA-ECMO support in high-risk pulmonary embolism: case report
Academic Article in Scopus
Despite the elevated mortality rates associated with high-risk pulmonary embolism (PE), this condition remains understudied. Data regarding the effectiveness and safety of invasive therapies such as venoarterial extracorporeal membrane oxygenation (VA-ECMO) in this patient population remains controversial. Here, we present the case of a 61-year-old male with high-risk PE associated with refractory cardiac arrest and cardiogenic shock who underwent a combination of extracorporeal cardiopulmonary resuscitation with VA-ECMO and pharmaco-invasive therapy (mechanical thrombi fragmentation plus lower alteplase dose), resulting in successful pulmonary reperfusion. After a prolonged in-hospital stay, the patient was discharged in stable condition. 2024 Gutierrez-Gallegos, Jimenez-Franco, Jerjes-Sanchez, Quevedo-Salazar, Rodriguez-Rivera, Paredes-Gutierrez, Lira-Lozano, Quintanilla-Gutierrez, Gomez-Gutierrez, de la Peña-Almaguer and Torre-Amione.
