abstract
- © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2021.Chemiluminescence (CL) is an eminent and significant analytical technique, because of its low background signal, simple readout methods, and inherent sensitivity, which make it a suitable choice for biosensors. This detection strategy can be used for miniaturization and integration in bio-microelectromechanical systems (BioMEMS) to develop low cost portable assays for point of care applications. This chapter provides a thorough review on the latest advancements of BioMEMS that operate based on the principle of CL detection. Among the provided examples, paper-based devices, microfluidic devices including lab-on-chip devices (LOC) and lab-on-compact-disk (LOCD) devices, and alternative techniques will be reviewed. A detailed comparison between the fabrication and operation of these devices along with the advantages and disadvantages of each technique are also included in this chapter.