Ensemble Method of Pre-Trained Models for Classification of Skin Lesion Images

abstract

Human beings are affected by different types of skin diseases worldwide. Automatic identification of skin disease from Dermoscopy images has proved effective for diagnosis and treatment to reduce fatality rate. The objective of this work is to demonstrate efficiency of three deep learning pre-trained models, namely MobileNet, EfficientNetB0, and DenseNet121 with ensembling techniques for classification of skin lesion images. This study considers HAM1000 dataset which consists of n = 10,015 images of seven different classes, with a huge class imbalance. The study has two-fold contributions for the classification methodology of skin lesions. First, modification of three pre-trained deep learning models for grouping of skin lesion into seven types. Second, Weighted Grid Search algorithm is proposed to address the class imbalance problem for improving the accuracy of the base classifiers. The results showed that the weighted ensembling method achieved a 3.67% average improvement in Accuracy, Precision, and Recall, 3.33% average improvement for F1-Score, and 7% average improvement for Matthews Correlation Coefficient (MCC) when compared to base classifiers. Evaluation of the model¿s efficiency and performance shows that it obtained the highest ROC-AUC score of 92.5% for the modified MobileNet model for skin lesion categorization in comparison to EfficientNetB0 and DenseNet121, respectively. The implications of the results show that deep learning methods and classification techniques are effective for diagnosis and treatment of skin lesion diseases to reduce fatality rate or detect early warnings. © 2025 by the authors.