abstract
- © 2020 Elsevier Ltd. All rights reserved.Detection of cancer at the early stages is important for its successful treatment. Electrospun nanofibers have emerged as a promising sensing platform for cancer-related bioanalytes which include nucleic acids, gene sequences, proteins, hormones, superoxide anion and even circulating cancer cells. Advantages of nanofibers include large surface areas, ease of functionalization, biocompatible nature, and variety of morphologies such as core-shell, porous and hollow nanofibers. Sensing platforms are majorly electrochemical based and further include fluorescent chemosensor and gas sensor. This manuscript provides a review of nanofiber-based technologies active for sensing cancer-related biomarkers.