abstract
- Exosomes, which are extracellular vesicles involved in transferring biomolecules between cells and tissues, hold great potential as diagnostic and therapeutic tools in cancer. However, there are challenges in bringing exosome technology to clinical practice. This work tackles these challenges through a multidisciplinary approach, focusing on enhancing exosome isolation, controlled delivery, and studying exosome biogenesis. Therefore, this work involves the development of microfluidic technology, a biomaterial-based delivery system, and a 3D cell culture model to study exosome biology. © 2023 Latin American and Caribbean Consortium of Engineering Institutions. All rights reserved.