abstract
- Biological methods and systems for lipid production remain crucial for multiple applications. Besides microalgae, oleaginous yeasts such as Schwanniomyces occidentalis could serve as an alternative biosystem for lipid production, although this oleaginous producer has been barely studied. Designing of different carbon (C) and nitrogen (N) supply strategies to a yeast culture, a first report on the yeast¿s parameters using a proposed mathematical model is presented, including an analysis of the model usefulness and the reliability limits of the estimated parameters. An assessment of S. occidentalis¿s potential for lipid production was conducted based on the modeling results and experimental data. The higher experimental lipid productivity obtained was 0.43 glip/L h with the lipids content in the biomass being around 0.24 mass fraction. The biomass productivity has reached around 1.49 gx/L h, which is high for this kind of cellular product. It is concluded that the model results allow accurate enough yeast culture projections useful in preliminary scale-up simulations and economic feasibility analysis of lipid production in further engineering studies and applications. © The Author(s), under exclusive licence to The Korean Society for Biotechnology and Bioengineering and Springer-Verlag GmbH Germany, part of Springer Nature 2025.