abstract
- © Springer Nature Switzerland AG 2019.The placenta is a key organ in pregnancy because during this period it supports normal fetal growth and development. The placenta is responsible for nutrient and oxygen transport to the fetus and also secretes several hormones and growth factors important for fetal development. An alteration in placental functions or development could lead to pregnancy disorders (preeclampsia, FGR, miscarriage, and gestational diabetes, among others). It is known that the placenta alters the expression levels of several placental biomarkers, ¿opening a door¿ to the study of such concentrations as prognostic factors of the aforementioned pregnancy disorders. Until now, although different placental biomarkers have been associated with pregnancy syndromes, no biomarker has been effectively used in clinical practice to diagnose and predict such diseases.