Educational programs for entrepreneurs of micro, small, and medium size enterprises (MSMEs) disseminate knowledge and skills for the existing businesses. This chapter aims to contribute to the effect of macroeconomic factors comprising innovation, technology, cost factors, and public policies on entrepreneurial promotion. The functional aspects of enterprises such as market competitiveness, design-to-market business modeling, and socio-economic wellbeing of small entrepreneurs in developing economies have been critically examined in this chapter. In particular, the double and triple helix effects concerning the business performance of the small enterprises have been discussed in the context of strategic alliances, innovation, technology, public policies, and the role of entrepreneurial education. Discussion in the chapter analyzes how these components related to MSMEs are being structured to improve their business performance and drive them competitive in the regional or global marketplace.
