Phaseolus vulgaris proteins as a source of biologically active peptides Book in Scopus uri icon

abstract

  • © 2018 Nova Science Publishers, Inc. All rights reserved. Common beans (Phaseolus vulgaris) are one of the world's most consumed crop with around 150 cultivars spread over America, Europe, and Asia. Beans are a reliable source of proteins, complex carbohydrates, vitamins, and minerals, contributing to diverse health benefits. Recently, proteins from vegetable sources, such as common beans, have been recognized to represent a very important source of biologically active peptides. These peptides encrypted in proteins are released by in vivo and In vitro digestion. Bioactive peptides are released by digestive enzymes (pepsin, pancreatin and trypsin), plant-derived proteases such as bromelain and papain, commercial enzymatic preparations such as Alcalase®, Flavourzyme®, Corolase®, Thermolysin® acting on Phaseolus protein isolates. Also, microorganisms used in solid or liquid fermentation can also produce bioactive peptides due to enzymes released into the culture media. Peptides obtained from the Phaseolus genus tend to have varied sizes, sequences, and unique activities, for instance, antihypertensive (due to angiotensin I-converting enzyme inhibition), antioxidant, anti-inflammatory, anti-diabetic, hypocholesterolaemic, antiproliferative and anticancer. This chapter provides information about the optimal In vitro conditions to produce peptides from common bean proteins, as well as the documented biological activities that potentiate the use of common beans as nutraceuticals to reduce the risks and/or prevent chronic-diseases.

publication date

  • November 14, 2018