selected publications academic article Anti-Ebola therapies based on monoclonal antibodies: Current state and challenges ahead 2015 Identification of Potential Therapeutic Targets for Cancer Stem Cell-Specific Combined Therapy through Gene Expression Profiling using Tumorsphere-Enriched Cultures of Prostate Cancer Cell Lines 2015 Attributes of potential entrepreneurs: An exploratory study on the perceptions of Latin American undergraduate students 2014 Collaboration in Entrepreneurial Biodiversity: The Case of Mexico 2014 Fine-tuning Entrepreneurship Education: how do Programs Impact Entrepreneurial characteristics in Students? 2014 Understanding potential entrepreneurs 2014 Measuring entrepreneurial competences 2014 Perfil del Emprendedor: Un Estudio Comparativo entre Estudiantes de Países de Iberoamérica 2014 The significance of the university environment for entrepreneurship education: A case study of an entrepreneurial university in Mexico 2014 Mathematical Modeling of the Serum Concentration of Norelgestromin and Ethinylestradiol Released by a Contraceptive Patch. 2014 Continuous monoclonal antibody production on a chip 2013 Scaling down the production of biopharmaceuticals to continuous micro-chips 2013 academic article in scopus Modeling COVID-19 epidemics in an Excel spreadsheet to enable first-hand accurate predictions of the pandemic evolution in urban areas. Scientific Reports. 11. 2021 Advances and prospective applications of 3D food printing for health improvement and personalized nutrition. Comprehensive Reviews in Food Science and Food Safety. 20:5722-5741. 2021 Portable and label-free quantitative loop-mediated isothermal amplification (Lf-qlamp) for reliable covid-19 diagnostics in three minutes of reaction time: Arduino-based detection system assisted by a ph microelectrode. Biosensors. 11. 2021 Social Non-profit Bioentrepreneurship: Current Status and Future Impact on Global Health. Frontiers in Public Health. 9. 2021 The presence of SARS-CoV-2 RNA in different freshwater environments in urban settings determined by RT-qPCR: Implications for water safety. Science of the Total Environment. 784. 2021 Fabrication of Multilayered Composite Nanofibers Using Continuous Chaotic Printing and Electrospinning: Chaotic Electrospinning. ACS Applied Materials & Interfaces. 13:37455-37465. 2021 Engineering bioactive synthetic polymers for biomedical applications: A review with emphasis on tissue engineering and controlled release 2021 Biofabrication of muscle fibers enhanced with plant viral nanoparticles using surface chaotic flows. Biofabrication. 13. 2021 Modeling vaccination strategies in an Excel spreadsheet: Increasing the rate of vaccination is more effective than increasing the vaccination coverage for containing COVID-19. PLoS ONE. 16. 2021 Controlling cellular organization in bioprinting through designed 3D microcompartmentalization. Applied Physics Reviews. 8. 2021 Advances in 3D bioprinting for the biofabrication of tumor models. Bioprinting. 21. 2021 Continuous chaotic bioprinting of skeletal muscle-like constructs. Bioprinting. 21. 2021 Serological test to determine exposure to SARS-CoV-2: ELISA based on the receptor-binding domain of the spike protein (S-RBDN318-V510) expressed in Escherichia coli. Diagnostics. 11. 2021 Colorimetric loop-mediated isothermal amplification (LAMP) for cost-effective and quantitative detection of SARS-CoV-2: The change in color in LAMP-based assays quantitatively correlates with viral copy number. Analytical Methods. 13:169-178. 2021 Bioinks for 3D Bioprinting: A Scientometric Analysis of Two Decades of Progress. International Journal of Bioprinting. 7:68-91. 2021 High-Throughput and Continuous Chaotic Bioprinting of Spatially Controlled Bacterial Microcosms. ACS Biomaterial Science and Engineering. 7:2408-2419. 2021 Strategies for antimicrobial peptide coatings on medical devices: a review and regulatory science perspective. Critical Reviews in Biotechnology. 41:94-120. 2021 Three-Dimensional Printing Using a Maize Protein: Zein-Based Inks in Biomedical Applications. ACS Biomaterial Science and Engineering. 7:3964-3979. 2021 Characterization of a novel automated microfiltration device for the efficient isolation and analysis of circulating tumor cells from clinical blood samples. Scientific Reports. 10. 2020 Carbon-Nanogold Hierarchical Micro/Nano Topographies for Cell Guidance. Advanced Materials Interfaces. 7. 2020 Characterization of chemically activated pyrolytic carbon black derived from waste tires as a candidate for nanomaterial precursor. Nanomaterials. 10:1-22. 2020 Expanding sacrificially printed microfluidic channel-embedded paper devices for construction of volumetric tissue models in vitro. Biofabrication. 12. 2020 Portable and accurate diagnostics for COVID-19: Combined use of the miniPCR thermocycler and a well-plate reader for SARS-CoV-2 virus detection. PLoS ONE. 15. 2020 Using chaotic advection for facile high-throughput fabrication of ordered multilayer micro-and nanostructures: Continuous chaotic printing. Biofabrication. 12. 2020 Nano-spaced Gold on Glassy Carbon Substrate for Controlling Cell Behavior. Advanced Materials Interfaces. 7. 2020 High-Throughput Automated Microscopy of Circulating Tumor Cells. Scientific Reports. 9. 2019 The tumor-on-chip: Recent advances in the development of microfluidic systems to recapitulate the physiology of solid tumors. Materials. 12. 2019 Validation of use of the miniPCR thermocycler for Ebola and Zika virus detection. PLoS ONE. 14. 2019 Ocular adhesives: Design, chemistry, crosslinking mechanisms, and applications. Biomaterials. 197:345-367. 2019 Analysis of the knowledge landscape of three-dimensional bioprinting in Latin America. International Journal of Bioprinting. 5:16-25. 2019 Chaotic printing: Using chaos to fabricate densely packed micro- and nanostructures at high resolution and speed. Materials Horizons. 5:813-822. 2018 Men who have sex with men and human immunodeficiency virus testing in dental practice Hombres que tienen sexo con hombres y detección del virus de la inmunodeficiencia humana en odontología. Gaceta Sanitaria. 32:262-268. 2018 Spatially and temporally controlled hydrogels for tissue engineering. Materials Science and Engineering: R: Reports. 119:1-35. 2017 Bioprinted Osteogenic and Vasculogenic Patterns for Engineering 3D Bone Tissue. Advanced healthcare materials. 6. 2017 Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation. ACS Nano. 11:5195-5214. 2017 Interplay between materials and microfluidics. Nature Reviews Materials. 2. 2017 Evaluation of changes in promoters, use of UCOES and chain order to improve the antibody production in CHO cells. Protein Expression and Purification. 132:108-115. 2017 Expansion mini-microscopy: An enabling alternative in point-of-care diagnostics. Current Opinion in Biomedical Engineering. 1:45-53. 2017 Potential gingival crevicular fluid and serum biomarkers by stage of HIV infection. Cytokine. 91:96-103. 2017 Anti-Ebola therapies based on monoclonal antibodies: current state and challenges ahead. Critical Reviews in Biotechnology. 37:53-68. 2017 Rapid Continuous Multimaterial Extrusion Bioprinting. Advanced Materials. 29. 2017 Delivery strategies to control inflammatory response: Modulating M1¿M2 polarization in tissue engineering applications. Journal of Controlled Release. 240:349-363. 2016 Using simple models to describe the kinetics of growth, glucose consumption, and monoclonal antibody formation in naive and infliximab producer CHO cells. Cytotechnology. 68:1287-1300. 2016 Hybrid Microscopy: Enabling Inexpensive High-Performance Imaging through Combined Physical and Optical Magnifications. Scientific Reports. 6. 2016 Strontium (Sr) and silver (Ag) loaded nanotubular structures with combined osteoinductive and antimicrobial activities. Acta Biomaterialia. 31:388-400. 2016 Examining entrepreneurial attributes of Latin American female university students. Gender and Education. 28:148-166. 2016 In vivo anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica (L.) Mill cladodes. Industrial Crops and Products. 76:803-808. 2015 High loaded dendrimers with free peripheral groups. Tetrahedron Letters. 56:6803-6806. 2015 Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels. Biomaterials. 73:254-271. 2015 Amino acid consumption in naïve and recombinant CHO cell cultures: producers of a monoclonal antibody. Cytotechnology. 67:809-820. 2015 Antibody derived peptides for detection of Ebola virus glycoprotein. PLoS ONE. 10. 2015 Enrichment of the cancer stem phenotype in sphere cultures of prostate cancer cell lines occurs through activation of developmental pathways mediated by the transcriptional regulator ¿Np63¿. PLoS ONE. 10. 2015 Supercritical CO2 foaming of thermoplastic materials derived from maize: Proof-of- concept use in mammalian cell culture applications. PLoS ONE. 10. 2015 Molecular evolution and expression profile of the chemerine encoding gene RARRES2 in baboon and chimpanzee. Biological Research. 48. 2015 Induction of Apoptosis in Colon Cancer Cells Treated with Isorhamnetin Glycosides from Opuntia Ficus-indica Pads. Plant Foods for Human Nutrition. 69:331-336. 2014 Studying mixing in Non-Newtonian blue maize flour suspensions using color analysis. PLoS ONE. 9. 2014 Continuous flow micro-bioreactors for the production of biopharmaceuticals: The effect of geometry, surface texture, and flow rate. Lab on a Chip. 14:1320-1329. 2014 Mathematical modeling of the release of active ingredients from a contraceptive patch: Ortho Evra® as a case study. Iranian Journal of Pharmaceutical Research. 13:39-48. 2014 Toxicity of flue gas components from cement plants in microalgae CO2 mitigation systems. Journal of Applied Phycology. 26:357-368. 2014 A Colorful Mixing Experiment in a Stirred Tank Using Non-Newtonian Blue Maize Flour Suspensions. Journal of Chemical Education. 91:1729-1735. 2014 Developing entrepreneurial competences in students in the life sciences: The Lifetech Ad-Venture program. On the Horizon. 22:182-191. 2014 The simplest stirred tank for laminar mixing: Mixing in a vessel agitated by an off-centered angled disc. AICHE Journal. 59:3092-3108. 2013 A baseline process for the production, recovery, and purification of bacterial influenza vaccine candidates. Biotechnology Progress. 29:896-908. 2013 Microplates as a microreactor platform for microalgae research. Biotechnology Progress. 29:638-644. 2013 A biopharmaceutical plant on a chip: Continuous micro-devices for the production of monoclonal antibodies. Lab on a Chip. 13:1243-1246. 2013 A simple eccentric stirred tank mini-bioreactor: Mixing characterization and mammalian cell culture experiments. Biotechnology and Bioengineering. 110:1106-1118. 2013 Application of eccentrically agitated stirred tanks in biotechnology settings: Examples, advantages, and challenges 2012 Enhancement of cell adhesion and proliferation through surface roughness modification in CHO cell cultures in PMMA-PDMS micro-devices 2012 Clinical and epidemiological features of 2009 pandemic H1N1 influenza differ slightly according to seroprevalence status during the second wave in the general population in México. Respiratory Care. 57:1586-1593. 2012 State-of-the-art in downstream processing of monoclonal antibodies: Process trends in design and validation. Biotechnology Progress. 28:899-916. 2012 A simple mathematical model based on the cancer stem cell hypothesis suggests kinetic commonalities in solid tumor growth. PLoS ONE. 7. 2012 Effect of different agitation systems and protocols on the growth of Nicotiana tabacum cells: Comparison of growth kinetics in Erlenmeyer flasks, conventional stirred tanks, and eccentrically agitated tank bioreactors 2011 Gene expression profiling of CD133 + prostate cancer stem cells induced from PC3 carcinoma cell line cultures 2011 Seroprevalence of antibodies to influenza A/H1N1/2009 among transmission risk groups after the second wave in Mexico, by a virus-free ELISA method. International Journal of Infectious Diseases. 15. 2011 Use of a plackett-burman statistical design to determine the effect of selected amino acids on monoclonal antibody production in CHO cells. Biotechnology Progress. 27:1709-1717. 2011 Effect of different agitation systems and protocols on the growth of Nicotiana tabacum cells: Comparison of growth kinetics in erlenmeyer flasks, conventional stirred tanks, and eccentrically agitated tank bioreactors 2011 Effect of different agitation systems and protocols on the growth of Vicotiana tabacum cells: Comparison of growth kinetics in erlenmeyer flasks, conventional stirred tanks, and eccentrically agitated tank bioreactors 2011 Gene expression profiling of CD133+ prostate cancer stem cells induced from PC3 carcinoma cell line cultures 2011 The receptor-binding domain of influenza virus hemagglutinin produced in Escherichia coli folds into its native, immunogenic structure. Journal of Virology. 85:865-872. 2011 Kinetic analysis and mathematical modeling of growth and lactic acid production of Lactobacillus casei var. rhamnosus in milk whey. Journal of Dairy Science. 93:5552-5560. 2010 Specific recognition of influenza A/H1N1/2009 antibodies in human serum: A simple virus-free ELISA method. PLoS ONE. 5. 2010 An Influenza A/H1N1/2009 hemagglutinin vaccine produced in Escherichia coli. PLoS ONE. 5. 2010 Compact cancer biomarkers discovery using a swarm intelligence feature selection algorithm. Computational Biology and Chemistry. 34:244-250. 2010 Effect of decortication and protease treatment on the kinetics of liquefaction, saccharification, and ethanol production from sorghum. Journal of Chemical Technology and Biotechnology. 85:1122-1129. 2010 Hydrodynamic conditions induce changes in secretion level and glycosylation patterns of Von Willebrand factor (vWF) in endothelial cells. Journal of Bioscience and Bioengineering. 109:400-406. 2010 Production of probiotic biomass (Lactobacillus casei) in goat milk whey: Comparison of batch, continuous and fed-batch cultures. Bioresource Technology. 101:2837-2844. 2010 Human hematopoietic progenitor cells grow faster under rotational laminar flows.. Biotechnology Progress. 26:1465-1473. 2010 patent Iniciadores y Sondas para la amplificación y detección molecular de ARN del Virus de la Influenza tipo A H1N1 brote 2009 2017 Proceso para la producción de L-Lactato mediante fermentación de lactosuero con lactococcus lactis subespecie lactis 2016 Proceso para producción de L-lactato mediante fermentación de lactosuero con lactoccoccus lactis subespecie lactis 2016 Proceso De Alto Rendimiento Para La Produccion De Biomasa Probiotica De Bacterias Lacticas A Partir De Suero De Leche No Suplementado 2015 Sistema de agitación inducida por una plataforma de movimiento rotacional concéntrico para cultivo de células y tejidos. 2015 63. Inmunoensayo para determinar la cantidad de anticuerpos específicos contra Influenza A-H1N1 en muestras de suero sanguíneo. 2015 Materiales termoplastificados derivados de proteínas de cápside viral recombinantes, su uso como vacunas de liberación prolongada, y su proceso de fabricación 2015 USO DE ANTÍGENOS RECOMBINANTES DIMÉRICOS PRODUCIDOS EN Escherichia coli PARA DETERMINAR LA CANTIDAD DE ANTICUERPOS ESPECIFICOS CONTRA VIRUS DE INFLUENZA EN MUESTRAS DE SUERO SANGUÍNEO 2014 "MICRO-REACTORES CONTINUOS DE CANAL PARA LA PRODUCCION DE BIOFARMACOS EN CELULAS DE OVARIO DE HAMSTER CHINO" 2014 Micro-reactores continuos compartametalizados para la producción de biofarmacos en celulas de ovario de hamster chino 2014 Dendrimeros y Dendrones Multifuncionales con alta capacidad de carga 2014 Dispositivo electronico de iluminación controlada para el estudio de Microorganismos fotosintéticos y/o materiales fotosensibles o fotoresponsivos 2013 Dispositivo electronico de iluminación controlada para el estudio de Microorganismos fotosintéticos y/o materiales fotosensibles o fotoresponsivos 2013 Multifuncional dendrons and dendrimers with high loading capacity 2013 Multifunctional dendrons and dendrimers with High loading capacity 2013 Método para obtener en Pichia pastoris proteinas recombinantes con capacidad ADN polimerasa 2013 Método para obtener proteínas recombinantes con capacidad inmunogenica en Pichia pastoris y su uso en una preparación de vacunas contra virus de influenza 2013
Expertise ODS Clean water and sanitation ODS Health & Wellness ODS Sustainable cities and communities ODS
other research activities Cáncer en un chip: Medicina personalizada del cáncer y evaluación de fármacos anti-cáncer en micro-dispositivos continuos Sistema microbiota-tumor en chip: desarrollo de un dispositivo microfluídico para estudiar interacciones entre la microbiota humana y esferoides de cáncer colorectal.
teaching activities Advanced Topics in Bioprocesses Assisted Research Bioreaction and Bioreactors Engineering Bioreactors Doctoral Dissertation: Defense Research Seminar Doctoral Research Engineering Innovation Design Project Integrated Exam Integration Project in Chemistry and Nanotechnology Methodologies for Innovation Pharmaceutical Bioengineering Product and Service Engineering Professional Experience Internship Research Intership Research Proposal Research Seminar Thesis
education and training Biochemical engineer, Tecnológico de Monterrey Doctor of Philosophy, Rutgers The State University of New Jersey Master in Science, Rutgers The State University of New Jersey Master of Science with a specialty in Chemical Engineering, Tecnológico de Monterrey