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Castorena-Torres, Fabiola

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Dr. Castorena Torres is Chemist-Pharmacobiologist graduated from the Autonomous Metropolitan University, and she obtained her Master and PhD degrees in Science in Toxicology from the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), unit Zacatenco in Mexico City. Dr. Castorena conducted a research stay in the area of Molecular Biomedicine of CINVESTAV-IPN, Monterrey unit. In addition, she was a post-doctoral researcher in the Biotechnology Department of Tecnológico de Monterrey (ITESM) with the Cardiovascular Medicine group. Currently, Dr. Castorena Torres is a full-time Professor-researcher at the School of Medicine and Health Sciences and Coordinator of the Graduate Program in Biomedical Sciences of the ITESM. Dr. Castorena is a member of the National System of Researchers (Level 1) from the National Council on Science and Technology, Mexico. Dr. Castorena has published 19 articles in international scientific journals indexed with impact factor, 3 book chapters and has participated in 26 national and international conferences in the biomedical area. Her work as a researcher is focused in the evaluation of peptides with antioxidant and anticancer activity using cellular models, and the use of animal models for the search of therapeutic targets to evaluate new molecules in the treatment of different diseases, including therapeutic alternatives for premature newborns affected by exposure to supplemental oxygen. Finally, he carries out studies with genetic factors associated with metabolism. Most recent publications: 1. Becerril-Esquivel C, Peñuelas-Urquides K, Blancas-Sánchez E, Zapata-Benavides P, Silva-Ramírez B, Chávez-Reyes A, Castorena-Torres F, Cisneros B, Bermúdez de León M. The polyaromatic hydrocarbon ?-naphthoflavone alters binding of YY1, Sp1, and Sp3 transcription factors to the Dp71 promoter in hepatic cells. Mol Med Rep. 2018 Apr;17(4):6150-6155. 2. Díaz-Gómez JL, Ortíz-Martínez M, Aguilar O, García-Lara S, Castorena-Torres F. Antioxidant Activity of Zein Hydrolysates from Zea Species and Their Cytotoxic Effects in a Hepatic Cell Culture. Molecules. 2018 Feb 2;23(2). 3. Aguirre-Vázquez A, Sampayo-Reyes A, González-Escalante L, Hernández A, Marcos R, Castorena-Torres F, Lozano-Garza G, Taméz-Guerra R, de León MB. Selenite restores Pax6 expression in neuronal cells of chronically arsenic-exposed Golden Syrian hamsters. Acta Biochim Pol. 2017;64(4):635-639. 4. Díaz-Gómez JL, Castorena-Torres F, Preciado-Ortiz RE, García-Lara S. Anti-Cancer Activity of Maize Bioactive Peptides. Front Chem. 2017 Jun 21;5:44. 5. Martínez LM, Videa M, López Silva T, Castro S, Caballero A, Lara-Díaz VJ, Castorena-Torres F. Two-phase amorphous-amorphous solid drug dispersion with enhanced stability, solubility and bioavailability resulting from ultrasonic dispersion of an immiscible system. Eur J Pharm Biopharm. 2017 Oct;119:243-252. Webpage: https://www.researchgate.net/profile/Fabiola_Castorena
Dr. Castorena Torres is Chemist-Pharmacobiologist graduated from the Autonomous Metropolitan University, and she obtained her Master and PhD degrees in Science in Toxicology from the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), unit Zacatenco in Mexico City. Dr. Castorena conducted a research stay in the area of Molecular Biomedicine of CINVESTAV-IPN, Monterrey unit. In addition, she was a post-doctoral researcher in the Biotechnology Department of Tecnológico de Monterrey (ITESM) with the Cardiovascular Medicine group. Currently, Dr. Castorena Torres is a full-time Professor-researcher at the School of Medicine and Health Sciences and Coordinator of the Graduate Program in Biomedical Sciences of the ITESM. Dr. Castorena is a member of the National System of Researchers (Level 1) from the National Council on Science and Technology, Mexico. Dr. Castorena has published 27 articles in international scientific journals indexed with impact factor, 3 book chapters and has participated in 29 national and international conferences in the biomedical area. Her work as a researcher is focused on the evaluation of the use of animal models for the search of therapeutic targets to evaluate new molecules in the treatment of different diseases, including therapeutic alternatives for premature newborns. Finally, she carries out studies with genetic factors associated with metabolism and she conducts collaborative studies on issues related to genetic factors associated with metabolism, and adverse effects of drugs in different pathologies in human population. Most recent publications: -Guzmán-Navarro G, León MB, Martín-Estal I, Durán RC, Villarreal-Alvarado L, Vaquera-Vázquez A, Cuevas-Cerda T, Garza-García K, Cuervo-Pérez LE, Barbosa-Quintana Á, Pérez-Saucedo JE, Lara-Díaz VJ, Castorena-Torres F. (2021). Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model. Exp Biol Med (Maywood). Mar;246(6):695-706. -Martín-Estal I, Castilla-Cortázar I, Castorena-Torres F. (2021). The Placenta as a Target for Alcohol During Pregnancy: The Close Relation with IGFs Signaling Pathway. Rev Physiol Biochem Pharmacol.180:119-153. doi: 10.1007/112_2021_58. -Bermúdez de León M, León-Cachón RBR, Silva-Ramírez B, González-Ríos RN, Escobedo-Guajardo B, ... Castorena-Torres F, Alcocer-González JM, Elizondo G, Salinas-Martínez AM. (2020) Association study of genetic polymorphisms in proteins involved in oseltamivir transport, metabolism, and interactions with adverse reactions in Mexican patients with acute respiratory diseases. Pharmacogenomics J. Aug;20(4):613-620. doi: 10.1038/s41397-020-0151-8. -Katia Peñuelas-Urquides, Mario Abelardo Bermúdez de León, Beatriz Silva-Ramírez, Fabiola Castorena-Torres, ...Licet Villarreal-Treviño, Salvador Said-Fernández. (2021) Two new dihydrosphingosine analogues against Mycobacterium tuberculosis affect gltA1, lprQ and rpsO expression, by published in Frontiers in Microbiology, section Antimicrobials, Resistance and Chemotherapy.Front.Microbiol.03 https://doi.org/10.3389/fmicb.2021.742867 -Ramírez-Flores PN, González-Villasana V, Garza-González JN, Silva-Ramírez B, Castorena-Torres F, Bermúdez de León M. (2021) Isotretinoin and Thalidomide Down-Regulate c-MYC Gene Expression and Modify Proteins Associated with Cancer in Hepatic Cells. Molecules. Sep 22;26(19):5742. -Aguirre-Vázquez A, Salazar-Olivo LA, Flores-Ponce X, Arriaga-Guerrero AL, Garza-Rodríguez D, Camacho-Moll ME, Velasco I, Castorena-Torres F, Dadheech N, Bermúdez de León M. (2021). 5-Aza-2'-Deoxycytidine and Valproic Acid in Combination with CHIR99021 and A83-01 Induce Pluripotency Genes Expression in Human Adult Somatic Cells. Molecules. Mar 29;26(7):1909. Webpage: https://www.researchgate.net/profile/Fabiola_Castorena
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