alex.aguilar@tec.mx
selected publications
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academic article
- A case of study on the optimization of a generic continuous aqueous two-phase systems pilot plant 2014
- A first approach for the up scaling and implementation of a generic continuous aqueous two-phase systems prototype for biomolecules extraction 2014
- Micro device approach for high throughput selection (HTS) and characterization of aqueous two-phase systems (ATPS) for continuous recovery of biological products and scaling strategy 2014
- Evaluation of chaotic advection micromixers embedded in microfluidic devices for high throughput characterization of aqueous-two phase systems. 2014
- Contnuous biological products extraction in aqueous two phase system 2013
- Evaluation of chaotic advection micromixers embedded in microfluidic devices for high throughput characterization of aqueous two-phase systems. 2013
- Contniuous biological products extraction in aqueous-two phase systems. 2013
- Partition of biomolecules using aqueous two pahse systems: comparison of bathc and continuous processes 2013
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academic article in scopus
- Pegylated species separation through an innovative PEG-grafted agarose-based resin, association quantified by microcalorimetry. Separation and Purification Technology. 253. 2020
- High Pressure Processing of Lipase (Thermomyces lanuginosus): Kinetics and Structure Assessment. European Journal of Lipid Science and Technology. 122. 2020
- Progress and Challenges in PEGylated Proteins Downstream Processing: A Review of the Last 8 Years. International Journal of Peptide Research and Therapeutics. 26:333-348. 2020
- Research-based learning as a strategy for the integration of theory and practice and the development of disciplinary competencies in engineering. International Journal on Interactive Design and Manufacturing. 13:1331-1340. 2019
- Electrokinetic assessment of RNase A species and innovative PEG-grafted agarose-based resins used in downstream processing of PEGylated proteins. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 577:562-569. 2019
- Protein A chromatography: Challenges and progress in the purification of monoclonal antibodies. Journal of Separation Science. 42:1816-1827. 2019
- Suppressing non-specific binding of proteins onto electrode surfaces in the development of electrochemical immunosensors. Biosensors. 9. 2019
- Factorial and economic evaluation of an aqueous two-phase partitioning pilot plant for invertase recovery from spent brewery yeast. Frontiers in Chemistry. 6. 2018
- Antioxidant activity of Zein hydrolysates from zea species and their cytotoxic effects in a hepatic cell culture. Molecules. 23. 2018
- Antiproliferative effect of peptide fractions isolated from a quality protein maize, a white hybrid maize, and their derived peptides on hepatocarcinoma human HepG2 cells. Journal of Functional Foods. 34:36-48. 2017
- Integration of cell harvest with affinity-enhanced purification of monoclonal antibodies using aqueous two-phase systems with a dual tag ligand. Separation and Purification Technology. 173:129-134. 2017
- Carotenoids extraction from Rhodotorula glutinis cells using various techniques: A comparative study. Indian Journal of Experimental Biology. 55:479-484. 2017
- Ultra-rapid and low-cost fabrication of centrifugal microfluidic platforms with active mechanical valves. RSC Advances. 7:55400-55407. 2017
- An integrated process for the in situ recovery of prodigiosin using micellar ATPS from a culture of Serratia marcescens. Journal of Chemical Technology and Biotechnology. 91:2896-2903. 2016
- Lycopene: Progress in microbial production. Trends in Food Science and Technology. 56:142-148. 2016
- Effect of mineral supplementation and type of starch on the production of prodigiosin from a culture of Serratia marcescens BS303 Efecto de la suplementación mineral y el tipo de almidón en la producción de prodigiosina a partir de un cultivo de Serratia marcescens BS303. Revista Mexicana de Ingeniera Quimica. 15:299-310. 2016
- An integrated practical implementation of continuous aqueous two-phase systems for the recovery of human IgG: From the microdevice to a multistage bench-scale mixer-settler device. Biotechnology Journal. 11:708-716. 2016
- A microdevice assisted approach for the preparation, characterization and selection of continuous aqueous two-phase systems: From micro to bench-scale. Lab on a Chip - Miniaturisation for Chemistry and Biology. 16:2662-2672. 2016
- Use of modified phenolic thyme extracts (thymus vulgaris) with reduced polyphenol oxidase substrates as anthocyanin color and stability enhancing agents. Molecules. 20:22422-22434. 2015
- Production and optimization of a chlorophyl-free leaf protein concentrate from alfalfa (Medicago sativa) through aqueous two-phase system Producción y optimización de un concentrado de proteína de alfalfa (Medicago sativa) libre de clorofila mediante sistemas de dos fases acuosas. Revista Mexicana de Ingeniera Quimica. 14:383-392. 2015
- Continuous enzyme aqueous two-phase extraction using a novel tubular mixer-settler in multi-step counter-current arrangement. Separation and Purification Technology. 141:263-268. 2015
- Chemical grafting of Sepharose 6B and its use in the purification of PEGylated RNase A. Separation and Purification Technology. 136:190-198. 2014
- Continuous aqueous two-phase systems devices for the recovery of biological products. Food and Bioproducts Processing. 92:101-112. 2014
- Low-abundant protein extraction from complex protein sample using a novel continuous aqueous two-phase systems device. Journal of Separation Science. 36:391-399. 2013
- Aqueous two-phase affinity partitioning systems: Current applications and trends. Journal of Chromatography A. 1244:1-13. 2012
- Study of biomolecules partition coefficients on a novel continuous separator using polymer-salt aqueous two-phase systems. Separation and Purification Technology. 78:69-75. 2011
- Application of an aqueous two-phase systems strategy for the potential recovery of a recombinant protein from alfalfa (Medicago sativa). Separation and Purification Technology. 77:94-98. 2011
- Current advances in the non-chromatographic fractionation and characterization of PEGylated proteins. Journal of Chemical Technology and Biotechnology. 86:18-25. 2011
- Biomass-adsorbent adhesion forces as an useful indicator of performance in expanded beds. Separation Science and Technology. 45:2335-2344. 2010
- Coupled application of aqueous two-phase partitioning and 2d-electrophoresis for characterization of soybean proteins. Separation Science and Technology. 45:2210-2225. 2010
- Aqueous two-phase systems strategies for the recovery and characterization of biological products from plants. Journal of the Science of Food and Agriculture. 90:1385-1392. 2010
- Characterization of green-tissue protein extract from alfalfa (Medicago sativa) exploiting a 3-D technique. Journal of Separation Science. 32:3223-3231. 2009
- Tridimensional soy protein characterization using two dimensional electrophoresis and partition in aqueous phases Caracterización tridimensional de proteínas de soya mediante electroforesis de dos dimensiones y partición en fases acuosas. Revista Mexicana de Ingeniera Quimica. 8:57-65. 2009
- Extraction and purification of bioproducts and nanoparticles using aqueous two-phase systems strategies. Chemical Engineering and Technology. 31:838-845. 2008
- Processing of soybean (Glycine max) extracts in aqueous two-phase systems as a first step for the potential recovery of recombinant proteins. Journal of Chemical Technology and Biotechnology. 83:286-293. 2008
- Direct comparison between ion-exchange chromatography and aqueous two-phase processes for the partial purification of penicillin acylase produced by E. coli. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 835:77-83. 2006
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chapter
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chapter in scopus
- Aqueous two-phase systems for cleanup and recovery of enzymes from plants and plant-derived extracts. Methods in Molecular Biology. 65-79. 2021
- Aqueous Two-Phase Systems for the Recovery and Purification of Bioproducts from Plants and Vegetable Tissues. 123-140. 2017
- Continuous Aqueous Two-Phase System Processes. 141-159. 2017
- Case studies in the application of aqueous two-phase processes for the recovery of high value biological products. ACS Symposium Series. 33-50. 2013
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patent